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ERA Test

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ERA Test

What is ERA Test?

In the Era of personalized medicine, a "one size fits all" policy is no longer acceptable. In IVF individualized ovarian stimulation, protocols are being promoted to optimize treatment. ERA is a step forward in improving IVF results through identification of the WOI and personalizing embryo transfer. The test has been shown to be accurate and reproducible and does not have the limitation of inter cycle variability.

Endometrial Receptivity Array or ERA is a test to check the endometrial receptivity. This is a genetic test that determines whether the endometrial lining is developed enough to receive the embryo for implantation. To analyze the endometrial receptivity, this new technology detects the expression of the 238 genes that are related to endometrial receptivity. This test assesses the optimal time to place an embryo that would help in a successful implantation and pregnancy hence it is also called as Personalised Embryo transfer.

There are many reasons as to why an IVF fails and endometrial receptivity could be one of the main reasons. The endometrial lining is a soft tissue in the uterus along which the cell is planted and the condition of the endometrium lining is crucial to a successful pregnancy.

  • When is this test done ?

    Patients who have had 2 or more unsuccessful embryo transfers Patients who have had concerns with endometrial lining (example: thin endometrial lining)

    Patients who have had had unsuccessful implantation with high quality embryos.

    Patients fall in the age group of 37 years or older are recommended an ERA test

    In general, any patient who has gone through an IVF treatment could be favored by her endometrial diagnosis previous to receiving her embryos

    The ERA test has been found to improve global pregnancy rates up to 73% in the personalized transfers made according to the test results (Fertility and Sterility, September 2013).

  • Benefits of ERA

    The Endometrial Receptivity Analysis has proved to be the most beneficial and accurate in determining the implantation window compared to other methods.
    The ERA test has increased chances of pregnancies as with the test, the doctors can determine the receptivity of the uterus lining and implant the embryo when chances of implantation are most likely. The precision of time saves failures and ensures successful pregnancy.
    The ERA test has saved a lot of time of couples opting for IVF. A lot of time gets wasted when a cycle of IVF fails and starting a fresh cycle. Now with this process, the time lag of month is eliminated. Couples can be free from the constant hope of a successful pregnancy and having a baby. After this test, success is ensured in the very next cycle.
    The IVF treatment is very costly and several cycles in anticipation of a pregnancy cost a lot. The test saves money by preventing further cycles and increasing probability of pregnancy.
    Above all, the process of IVF is not only physically painful but also mentally taxing. Numerous cycles take a toll on the overall health of the patient and this test gets rid of such problems, as the doctors would now know the right time to implant the embryo

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